Clinical Proof
ZO® Skin Health is one of a select few professional skin care lines with a broad range of medical grade skincare comprising advanced skincare protocols and products that prevent aging and offer exceptional skin protection from environmental damage. ZO’s therapeutic treatment protocols and highly effective targeted skin care solutions help reinforce and maintain optimal skin health. Based on the latest scientific advances in skin therapy technologies, our products and protocols help physicians provide continuous skin health care for all skin types, genders and ages.
Skincare Product Innovation
At ZO® Skin Health, we believe that the only way to achieve optimal skin health is through the power of science. Founded by world-renowned dermatologist Dr. Zein Obagi, we push the boundaries of medical grade skincare by providing the most innovative skincare products powered by cutting-edge formulas and technologies. Our products and protocols are clinically recognized for their exceptional efficacy as some of the best skin care for aging skin – suitable for maintaining skin health for anyone, regardless of age, ethnicity, unique skin condition or skin type.
Proprietary Technologies
ZO® Skin Health’s technological expertise sets us apart. Our proprietary technologies are core to the development of formulations that achieve superior outcomes. ZO® technologies are multi-modal, allowing for the most comprehensive approach to skin health, and are always paired with a delivery system that enables greater penetration and precision. From skin firming ZCORE™ to complete skin protection with Triple- Spectrum Protection™ and our award-winning retinol skin brightener formulations, our products and protocols address the most serious skin concerns at every stage of life.





Research + Development
ZO® Skin Health’s Research and Development team focuses on finding unique ingredients that work synergistically to deliver innovative products that our physicians and patients expect from a medical grade skincare brand. Through a combination of professional collaborations, higher education partnerships and unrivaled technical expertise, our R&D team continues to deliver exceptional industry-leading products and protocols for patent-worthy results.
Clinical Studies
ZO® Skin Health’s extensive clinical studies demonstrate the exceptional efficacy of the ZO®Skin Health portfolio of products and protocols. Capturing real results from real patients, our scientific analyses demonstrate our ongoing commitment to the ZO® philosophy that skin health can and should be supported by science.
Hydrating Crème
Hydration
89% of patients showed significant improvement in skin hydration by week 4.
Redness
70% of patients showed significant improvement in the appearance of redness by week 8.
Texture + Smoothness
100% of patients showed significant improvement in texture and smoothness by week 8.
Itching
82% of patients reported diminished itching due to increased hydration by week 8.
Firming Serum
Elasticity
Firming Serum is clinically proven to improve the appearance of firmness.
97% of participants showed significant improvement in skin firmness by week 12.
Firmness
Firming Serum is clinically proven to improve the appearance of firmness.
97% of participants showed significant improvement in skin firmness by week 12.
Sagging
Firming Serum is clinically proven to improve the appearance of sagging skin.
93% of participants showed significant improvement in the appearance of both mid-face and jawline skin sagging by week 12.
Wrinkle + Texture Repair
Hydrations
Wrinkle + Texture Repair is clinically proven to improve the skin’s ability to retain hydration.
Lines + Wrinkles
Wrinkle + Texture Repair is clinically proven to improve the appearance of lines and wrinkles.
98% of participants showed improvement in the appearance of crow’s feet and facial fine lines by week 12.
Texture
Wrinkle + Texture Repair is clinically proven to improve the appearance of smooth texture.
93% of participants showed improvement in skin texture by week 12.